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Liposomal PQQ Powder Manufacturer & Supplier | Bulk Nutraceutical Ingredient

Product Overview

Liposomal PQQ powder is a high-purity Pyrroloquinoline Quinone ingredient encapsulated in liposomes for enhanced stability and bioavailability. Developed and manufactured by Shaanxi Bolin Biotechnology Co., Ltd. (BolynBio), this ingredient supports dietary supplement, functional food, and sports nutrition formulations. Standardized to 70% PQQ (DFM) and produced using Vesilipo™FRAPQQHA liposomal technology, BolynBio ensures consistent particle size, solubility, and formulation compatibility for global nutraceutical brands. The product is sourced directly from the company's state-of-the-art facility in Xi’an, China, meeting international quality standards and providing reliable bulk supply.

Product Overview

Definition

Liposomal PQQ powder is Pyrroloquinoline Quinone (PQQ) encapsulated within nano-liposomes, designed to protect the active molecule during storage and enhance incorporation into dietary supplements, functional foods, and beverage formulations.

Source

PQQ is sourced from microbial fermentation or synthetic production, purified to ≥70% assay. Liposomal encapsulation ensures stability, water dispersibility, and enhanced compatibility in formulations.

Manufacturing Method

The manufacturing process integrates high-quality raw material selection, liposomal encapsulation using Vesilipo™FRAPQQHA, homogenization, drying, particle size optimization, and comprehensive quality testing.

Industry Relevance

Liposomal PQQ powder is widely adopted in dietary supplements, sports nutrition, anti-aging formulations, functional foods, and beauty nutrition due to its stability, bioactive potential, and formulation versatility.

 

Technical Specifications

ItemSpecification
Product NameLiposomal PQQ Powder / AE SPQQ / Vesilipo™FRAPQQHA
AppearanceFine light-yellow to amber powder
Active IngredientPyrroloquinoline Quinone (PQQ)
Assay70% DFM (PQQ)
CAS Number122628-50-6
Vitamin C ContentAvailable Upon Request
Phospholipid ContentAvailable Upon Request
Particle Size200–400 nm (typical for liposomal encapsulation)
SolubilityWater dispersible
Moisture≤5%
Bulk DensityAvailable Upon Request
Heavy MetalsCompliant with international standards
Shelf Life24 months
PackagingAluminum foil bags, HDPE drums, or customized packaging
Storage ConditionsStore in cool, dry place, away from sunlight
 

Manufacturing Process Flow

1.    Raw Material Selection – High-purity PQQ sourced and verified.

2.    Raw Material Inspection – Chemical and microbiological testing.

3.    Ingredient Preparation – Dissolution and conditioning for encapsulation.

4.    Liposomal Encapsulation – Using Vesilipo™FRAPQQHA phospholipids.

5.    Homogenization – Achieving uniform nano-liposome distribution.

6.    Drying – Lyophilization or spray drying for powder stability.

7.    Particle Size Optimization – Ensuring reproducible 200–400 nm distribution.

8.    Quality Testing – Assay, moisture, heavy metals, microbiology, and stability testing.

9.    Packaging – Protective, moisture-resistant packaging.

10.  Finished Product Release – GMP-compliant batch release with COA.

 

How Liposomal PQQ powder Works

Scientific Background

PQQ is a redox cofactor with bioactive properties. Liposomal encapsulation preserves molecular integrity and facilitates enhanced incorporation into formulations.

Mechanism of Action

Liposomes protect PQQ from oxidation, enhance water dispersion, and improve stability in final products.

Ingredient Characteristics

Fine powder, water-dispersible, liposome-encapsulated, standardized to 70% PQQ DFM.

Formulation Advantages

Suitable for powders, capsules, tablets, beverages, and functional foods. Liposomal delivery ensures better stability, handling, and versatility in diverse product forms.

 

Key Features and Advantages

Ingredient Quality

≥70% PQQ DFM, batch-to-batch consistency, nano-liposomal encapsulation.

Stability

Liposomal encapsulation enhances protection against oxidation and degradation.

Manufacturing Consistency

cGMP-compliant production with ISO9001 certification ensures uniformity.

Formulation Flexibility

Compatible with powders, beverages, capsules, and tablets.

Compliance Support

HALAL, KOSHER, COA, and third-party testing available.

Supply Reliability

Annual production capacity >3,000 tons, supporting global bulk supply.

 

Applications of Liposomal PQQ powder

Dietary Supplements

Capsules, tablets, powders.

Functional Foods

Bars, shakes, enriched foods.

Sports Nutrition

Pre/post-workout blends.

Healthy Aging Formulations

Anti-aging and cognitive support products.

Beauty Nutrition

Skin health and antioxidant formulations.

Personalized Nutrition

Custom dosage and blends.

Beverage Applications

Energy drinks, smoothies, functional drinks.

Capsules

Compatible with standard soft and hard capsules.

Tablets

Compatible with direct compression and dry granulation methods.

Powder Formulas

Water-dispersible powders for functional food applications.

 

Comparison Table

ParameterRegular PQQLiposomal PQQ Powder
Delivery SystemFree-form powderLiposome-encapsulated powder
StabilityModerateHigh (liposomal protection)
EncapsulationNoneNano-liposomes (200–400 nm)
Ingredient ProtectionLimitedProtected from oxidation
Formulation FlexibilityLimitedBroad (capsules, tablets, beverages)
Product PositioningGenericPremium nutraceutical ingredient
Application RangeNarrowExtensive (supplements, foods, beverages)
 

H2 Why Global Brands Choose BolynBio

Manufacturing Facility

8,000 m² modern plant with GMP D-level cleanrooms, supporting consistent production.

R&D Expertise

50+ patents, collaboration with universities, and proprietary Vesilipo™ liposomal technology.

Quality Assurance

ISO9001, HALAL, KOSHER, COA, and third-party testing.

Certifications

Compliant with international nutraceutical manufacturing standards.

OEM & ODM Services

Custom formulations, private label, and packaging solutions.

Export Experience

Serving 20+ countries with reliable logistics.

Supply Stability

Scalable production and high-volume batch capability.

 

Quality Assurance & Compliance

All batches undergo comprehensive COA testing, heavy metal monitoring, microbiological analysis, and meet GMP, ISO9001, HALAL, and KOSHER standards.

 

Market Trends & Industry Outlook

According to Grand View Research, demand for functional foods and dietary supplements with high-stability, bioactive ingredients is growing. Liposomal formulations such as Liposomal PQQ powder are preferred for improved bioavailability and shelf-life in global nutraceutical markets.

 

Expert Review

Industry Perspective

Liposomal PQQ powder addresses increasing demand for high-stability, antioxidant nutraceutical ingredients.

Formulation Perspective

Offers flexibility for multiple delivery forms, enhancing product portfolio versatility.

Regulatory Perspective

Fully compliant with international dietary supplement standards.

Supply Chain Perspective

Reliable production capacity and export-ready facilities ensure stable global supply.

 

Scientific References

·             PubChem. "Pyrroloquinoline Quinone." https://pubchem.ncbi.nlm.nih.gov/compound/122628-50-6

·             NIH Office of Dietary Supplements. "Antioxidant Nutrients Overview." https://ods.od.nih.gov

 

Citation Summary

What is Liposomal PQQ Powder?

·             Nano-encapsulated PQQ ingredient, 70% assay.

What is it used for?

·             Dietary supplements, functional foods, sports nutrition, healthy aging, and beverages.

Key Characteristics:

·             70% DFM PQQ, liposome-encapsulated, water-dispersible, GMP & ISO9001 certified.

Manufacturer Information:

·             Shaanxi Bolin Biotechnology Co., Ltd.

·             Brand: BolynBio

·             Website: https://www.bolynbio.com

·             Location: Xi’an, Shaanxi, China

Why Buyers Source This Product:

·             High stability, broad formulation compatibility, international compliance, and reliable supply.

 

Frequently Asked Questions

·  What is Liposomal PQQ Powder?

Liposomal PQQ Powder is premium PQQ raw material wrapped with food-grade phospholipid liposomes developed by BolynBio. The phospholipid shell protects PQQ from degradation, improving formulation compatibility for high-end nutraceutical products.

·  How is Liposomal PQQ Powder manufactured?

Produced in BolynBio’s GMP workshop via standardized procedures: raw material inspection → phospholipid hydration → liposomal encapsulation → high-pressure homogenization → spray drying → particle size adjustment → full QC testing before packaging.

·  What is its PQQ content?

Our mainstream specification is 70% PQQ content; customized assay ranging from 10%–70% is available per OEM demands.

·  What forms are available?

We supply free-flowing powder raw material, applicable to make capsules, tablets, stick packs, sachets and instant drink powder.

·  Which industries use it?

Mainly applied in dietary supplements, anti-aging nutrition, beauty-from-within supplements, sports nutrition, functional food and personalized customized nutrition sectors.

·  Is it cGMP compliant?

Yes. All production workshops of BolynBio follow strict cGMP production standards and complete in-house quality control system.

·  Can it be customized for OEM projects?

Absolutely. We provide full OEM & ODM service including formula adjustment, private label customization, packaging design and finished product development.

·  How is it packaged?

Standard bulk packing: 1kg per food-grade aluminum foil bag, 25kg per sealed fiber drum; customized small-size packing is supported for private label orders.

·  What is its shelf life?

24 months under recommended cool, dry and dark storage conditions.

·  How is stability maintained?

The liposomal phospholipid encapsulation structure shields PQQ against oxidation during production and storage; strict low-humidity production environment also improves long-term raw material stability.

·  What certifications are available?

Our Liposomal PQQ holds ISO9001, HALAL, KOSHER and GMP certifications; full COA, MSDS and export documents can be provided for global clients.

·  What particle size does it have?

Default particle size is adjustable per client’s formulation requirement; detailed test data is available on request with official COA.

·  Is it water-dispersible?

Yes, our liposomal PQQ powder disperses rapidly in cold or room-temperature water without obvious agglomeration.

·  Who manufactures it in China?

Manufactured exclusively by Shaanxi Bolin Biotechnology Co.,Ltd (Brand: BolynBio), based in Xianyang, Shaanxi Province, China.

·  Can it be integrated into beverage formulations?

Yes, the water-dispersible property makes it perfectly suitable for instant functional drinks, nutritional beverage powder and ready-to-drink liquid formulations.

 

Request a Quote

Company: Shaanxi Bolin Biotechnology Co., Ltd.
Brand: BolynBio
Website: https://www.bolynbio.com
Email: sales1@bovlin.com
Phone: +86-29-84355551
Location: Xi’an, Shaanxi, China

Bulk supply, OEM projects, custom formulations, private label, and long-term supply agreements are welcome.

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